King Charles has taped a first-hand account concerning his battle with cancer, set to air as part of this year's Stand Up To Cancer campaign, spearheaded by medical research organisations and a major network.
Buckingham Palace confirmed the King would reflect on his "recovery journey" as a person living with the disease, in a televised statement on Friday evening at 8pm UK time.
The recording, filmed within Clarence House recently, will highlight the critical nature of preventative health checks to help guarantee more people detect the disease at an early stage.
This constitutes a rare update on the wellbeing of the Monarch, who has been in a course of therapy since the news was shared in February 2024. But it is thought doubtful the King will identify his type of cancer.
The awareness event each year collects money for clinical trials and patient care and encourages people to get screenings to increase the chances of an early diagnosis.
The King's public discussion about his illness, and managing the disease, has been intended to raise awareness and to persuade more people to get checked - and this will be escalated with this unusual royal involvement.
Up until now the King's key philosophy to his cancer has been to maintain his duties, upholding a busy schedule in spite of his regular rounds of treatment, and he seems not to have wanted to be defined by his illness.
This year has seen the 77-year-old Monarch, undertaking several foreign visits, notably to Italy and Canada, and welcoming the largest volume of inward state visits to the UK for decades, including the German president in recent days.
This Friday's awareness show on the network, hosted by well-known figures such as several TV personalities, will encourage people not to be afraid of getting preventative tests.
The hosts have been affected by cancer - one host said in November she had had an operation for breast cancer, while Clare Balding was treated for thyroid cancer more than 15 years ago. Comedian Hills has previously discussed his parent, who had stomach cancer and then later leukaemia.
The programme will reach out to the estimated nine million people in the UK who charities estimate are not compliant with national health programmes, with an digital tool to let people check if they are eligible for tests for breast, bowel and cervical cancer.
In an effort to clarify cancer checks and show the benefit of timely identification there will be a real-time transmission from hospital departments at Addenbrooke's and Royal Papworth hospitals in Cambridge.
"My aim is to remove the anxiety out of cancer screening and show the public that they are not on their own in this," said Davina McCall.
At present in the UK, there are a number of national health screening services - for major health concerns - available to specific demographics.
A emerging preventative initiative is also being gradually implemented for anyone at potential risk of developing the condition, focusing on people of a certain age, who have a smoking history or used to.
Men may enquire about specific tests, but there is no national programme in place.
The fundraising campaign, which has raised a significant sum over the past decade, is funding 73 clinical trials encompassing many patients.
His Majesty, in a message for attendees at a reception for support groups in the spring, had spoken of understanding the "daunting and at times scary experience" for cancer sufferers and their loved ones.
But he said his experience of managing cancer had shown him that "periods of great challenge of disease can be illuminated by the kindness of others," as he thanked those who looked after cancer patients.
Royal representatives has not disclosed the specific type of cancer the King has, or the medical care he has received. The King's cancer was discovered following he had undergone a routine operation.